Jumat, 24 September 2010

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The Reluctant Royal

Ever-practical Maxwell Carter was used to designing highways and streets for VIP motorcades—not waving from the head limo! So when he discovered he was actually a prince of Chantaine by birth, he wasn't impressed—or interested in getting to know his royal family. But his assistant, Sophie Taylor, insisted he give the royals a chance—and Sophie was usually right!

As soon as she stepped into paradise and into the hands of Maxwell's matchmaking half sisters, staid Sophie became sexy Sophie. It wasn't long before a strictly business relationship became personal…as personal as another royal-baby-to-be! Would Maxwell's sense of duty doom their new love from the start, or could this reluctant prince fling caution to the wind and give his heart to his Cinderella?

  • Sales Rank: #216748 in eBooks
  • Published on: 2013-03-01
  • Released on: 2013-03-01
  • Format: Kindle eBook

About the Author
Leanne Banks is a New York Times bestselling author with over sixty books to her credit. A book lover and romance fan from even before she learned to read, Leanne has always treasured the way that books allow us to go to new places and experience the lives of wonderful characters. Always ready for a trip to the beach, Leanne lives in Virginia with her family and her Pomeranian muse.

Excerpt. © Reprinted by permission. All rights reserved.
"You have to go," Sophie Taylor insisted for the tenth time.

Glancing out the window of his temporary office trailer, Max Carter felt a sense of satisfaction at the sight of the finished bridge project. The new construction gleamed in the Australian sun as if it were shouting success.

"I've got too much to do," he said, turning to face his assistant of four years. "Paperwork, then it's on to the next project."

Sophie scowled at him. "You could take a short break. It's near the holidays. It wouldn't kill you. I can't believe you're dismissing this without giving it a second thought. They're your family."

Max rolled his eyes. There were few people he'd allow to argue with him this much, but Sophie had proven her value to him time and time again. He couldn't think of another woman he respected more. Even now as she frowned at him with softly accusing chocolate-brown eyes from behind her smudged glasses, he felt compelled to listen to her. He knew that beneath that curly mass of hair, she had a quick and fair mind.

"Why do you care so much about this? It's not your family," he said.

"I don't want you to have any regrets."

He sighed, remembering the day the two representatives of the Royal House of Devereaux had hunted him down on the job site. The words they'd said to him had been stuck in his brain like the annoying refrain of a song he couldn't make go away.

Your biological father was Prince Edward of Chan-taine.

"They're not my family, Sophie. I can't believe these royals are thrilled with the news that their father hatched a couple of extra children with a B-movie actress in America." Although Max had always known he was adopted, he never would have dreamed his biological parents were a prince and actress!

"What about Coco Jordan?" Sophie asked, referring to the other child the prince and actress had produced. "She's your sister. Don't you at least want to meet her? And, who knows, maybe she wants to meet you. You might try thinking about the feelings of someone other than yourself. Didn't you say both of your parents had passed away? She has no one now. No one except you."

"She doesn't have me," he retorted, but he felt an itchy sensation of obligation. "I wouldn't be able to pick her out of a crowd of two."

Her frown deepened. "Maybe you should just give her a chance."

Max sighed and glanced around the trailer that had become his temporary office and home. The LEGO rendering of the bridge sat next to his desk. A small Christmas tree blinked in the corner. Two stuffed puppies sat next to Sophie's desk. Sophie had complained many times over that she wanted a dog, but there was no way she could drag a pet to all the places Max had taken her for projects, many of which were international. From the first time she'd assisted him on a job, he'd learned she was the best assistant he could possibly have despite her complaints. He grumbled and she helped fix things. She anticipated his needs. Thank goodness he'd never given into any errant urges to have sex with her because he was certain that would have ruined the best relationship he'd ever had with a woman.

If she weren't his assistant, she might have been the perfect woman for him. Low-maintenance, undemanding and she wasn't at all clingy. Max, however, had Sophie's number. Underneath that practical veneer, Sophie was a romantic at heart. Even though she'd followed him around the world, he had an itchy, uncomfortable feeling that Sophie wanted a husband and baby to go along with that dog she so desired.

And with his past disastrous relationships with women, he'd learned to steer clear of women who wanted romance and home and hearth. "You're never gonna stop with this until I visit Chantaine," he said. "Are you?"

She looked at him from behind her glasses with un-apologetic determination. "Never. Ever."

"Okay. I'll go," he said. "For one day. Just one day and then you don't get to look at me with that guilty face."

Sophie gave a slight smile. "One day will be enough."

Max felt a sinking feeling at her expression. She looked like she knew something he didn't. That wasn't a good thing.

Max left the following day for the island country of Chantaine to meet his new relatives while Sophie wrapped up the loose ends of the contract. Terri Caldwell, one of the other assistants on the project, walked into the trailer.

"How's it going?"

"I'm halfway through a million pages of paperwork," Sophie said without looking up from her laptop.

"That's what you get for being so efficient and devoted," Terri teased. "And head over heels for Max Carter."

Sophie grimaced. Nearly a decade older than herself, Terri was a good woman from Arkansas, honest to a fault. Her husband was a truck driver back in the States, but they visited every chance they got. Terri had started taking the long-distance work to pay for her twin boys' college tuition. She had become a good friend to Sophie especially during the last couple of months. Terri was intuitive enough to spot Sophie's unrequited feelings for Max, and Sophie had grown to trust the woman's discretion. It had been a relief to have the older woman's sympathy. "Don't rub it in. I'll get over him someday. Maybe someday soon. I really want a King Charles spaniel and there's no way I can do that if I allow him to keep dragging me all over the world."

"What amazes me is that he doesn't seem to notice your feelings for him when everyone else can see it as plain as day," Terri said, leaning against Sophie's desk.

Sophie felt a jagged twist inside her. "He doesn't see me as a woman. He sees me as the ultimate assistant."

"Well, you are the ultimate assistant," Terri agreed with a nod. "But you're also a woman. Ever thought about giving him a clue about that?"

Sophie stopped keying in the final construction details and glanced up at Terri. "I'm not exactly sure how. I'm not the type to wear low-cut shirts or short skirts. Or lots of makeup. But I'm still feminine."

"Of course you are. I wonder if Max might belly up to the bar if he had a little competition."

Sophie shook her head. "That's not my way."

"Sometimes men need a little push. You may have to think outside the box. Unless you're okay with having unrequited love for the rest of your life."

Sophie sighed, remembering the first time she'd met Max. She'd been bowled over. He was the Indiana Jones of road construction. She'd quickly learned how to anticipate his professional needs. He'd learned, not quite as quickly, how valuable she could be to him. Though her feelings for him had deepened over the years, only his professional respect had grown for her, and nothing more.

Sophie had hoped and wished, but nothing romantic had developed between them. She'd watched Max engage in several quickie affairs that had brought her enormous pain. Somehow, his relationship with her had turned out to be his most long-lasting one with a woman. Except, he didn't really view her as a woman.

"Maybe with the holiday break, I can go back home and get my King Charles spaniel. Maybe then I'll get over him," Sophie said. "Not being around him could help me get over him."

"It would help if he weren't so good-looking," Terri said.

"I can get over the good-looking part, but he can be charming," Sophie said. "When he wants to be, he can be so damn charming."

"He can also be a toad. He's fine about making us all work long hours" Terri said.

"True, but he works longer than anyone else. And everyone is well-compensated. The real trouble for me is that he is charitable. He puts on this front about only caring about himself, but everywhere we go, he gets the crew involved in some kind of charity project." She pointed at the pile of wrapped gifts next to the Christmas tree. "For children stuck in the hospital over the holidays. If only he were as selfish and uncaring as he says he is."

"Have you gone out with another man since you've met Max?" Terri asked.

Self-consciousness burned through her. "Yes, I have," she said. "Four times. All during my vacations."

"Woo-hoo. Four times in four years." Terri shook her head. "I dare you to meet six new men over your holiday."

"How am I supposed to do that?"

"Online. You can arrange meet-ups in no time."

"I think I'd rather poke out my eye with a pencil," Sophie said under her breath.

"You gotta do something," Terri said. "You either need to pull that pony in or let him ride."

Max couldn't see much of the island country of Chantaine while soaring in the sky since he was arriving after dark. He'd run a computer search and caught a few images. Beautiful country that seemed to combine Greece's Mediterranean views, France's sophistication and Italy's charm. While he'd run the search, he'd also looked into his new so-called siblings. The eldest, Crown Prince Stefan, came across as a hard worker, more serious-minded than their biological father, Prince Edward. It appeared that their father had enjoyed yachting and living like a playboy, much more than ruling.

Max figured that his adopted parents' failed marriage was one more reason for him to never get married. They had fought more than they hadn't when his father had been around. When things got tough, which was quite frequent, his adoptive father would leave the house and desert Max's adoptive mother. He'd always been grateful for the home and opportunities his parents had provided for him, but their discord had bothered him the first time he'd heard them screaming at each other and doors slamming at night.

Now, Max not only had been given a bad example of marriage, he had the genetic material of a philanderer from Prince Edward.

He'd briefly checked out the rest of the Devereaux clan. The eldest sister, Valentina, lived in Texas with her rancher husband and their daughter. The second sister, Fredericka, lived in France with her movie producer husband. Princess Bridget was married to a doctor from the States and Princess Pippa had just married an international businessman. The youngest brother, Jacques, attended Oxford and played soccer.

Once he'd told the palace he would be coming, Prince Stefan's wife, Eve, had sent him a message asking him to keep his visit secret because she wanted his presence to be a surprise for Coco Jordan's wedding. The idea that he would be a surprise for anyone's wedding, let alone his full-blooded sister, made him squeamish, but he agreed to the plan.

The plane landed with a jolt, reminding him he was about to put himself in an insane situation. He thought of how Sophie had hounded him. After this brief visit, she wouldn't be able to look at him with her guilt gaze. Lord knew, he hated that guilt gaze.

A man approached him at the luggage carousel. "Mr. Carter? Mr. Maxwell Carter?"

Max nodded slowly. "Yes, and you?"

"I'm Mr. Bernard, an assistant to His Highness, Prince Stefan. We're happy that you're visiting Chantaine. Welcome to our country. If it pleases you, I have a driver ready to take you to a villa just outside the palace grounds. We would normally invite you to stay on the palace grounds itself, but with Miss Jordan's wedding taking place in a few days, Princesses Eve and Bridget have requested to keep your presence secret until the nuptials."

"Fine with me," he said reluctantly, and realized his one-day stay had just been extended.

Three days later, after several tours of the island, Max was escorted to the office of Crown Prince Stefan Devereaux. Now, pacing the office as he waited for his half brother, Prince Stefan, he felt the hard gaze of the palace security tracking every move he made. If the De-vereauxes were so insistent that he join them, then why did they look at him as if he were a potential assassin?

One moment later, a man stepped inside the room. "His Royal Highness, Prince Stefan," the man announced.

A dark-haired man wearing a black suit strode toward him and nodded. "Maxwell Carter?"

Max nodded. "Yes. Max. And what shall I call you? Your highness or Prince Stefan?"

Prince Stefan lifted his left eyebrow. "Stefan will do."

Max nodded again. "Stefan it is."

Stefan waved his hand to a chair facing the desk and then sank into the large chair behind the desk. "I appreciate that you have made an effort to come to Coco Jordan's wedding. Coco has made a huge effort to meet us…and now to meet you."

Max shrugged, uncomfortable with Stefan's gratitude. He'd expected the man to be more cold and pompous. "I haven't met any members of the family before now."

"You will before and after the ceremony," Stefan promised, glancing at his watch. "In fact, the girls should be stopping by any minute. My sisters have been fussing over Coco for the last few days. I'm sure you're curious to meet her."

"I suppose," Max said. "I have no idea what kind of person she is even though we share the same blood."

"Well, she's delightful," Stefan said. "Kind and compassionate. The kind of woman you would want as a sister."

"I'm impressed that you can say that after you have four sisters."

Stefan laughed. "Good point. My sisters do their best to keep me in line."

"And you?" Max asked.

"I do my best to keep them out of the equation," Stefan said. "I'm told you've had a chance to tour the island?"

Max nodded. "I have," he said. "It's a beautiful place, and because of my profession I notice the infrastructure. Most of the roads and bridges are in good condition except the north end of the island."

"I was going to ask you about that," Stefan said. "One of my brothers-in-law has expressed an interest in building a green retreat with an emphasis on the nature areas on that part of the island, but he and I agree that the roads currently can't sustain the possibility. We'd like to improve the roads, but keep the costs down."

"Isn't this something your government would pursue? I wouldn't have expected a royal to have interest in roads."

Stefan gave a shark-like smile. "Then you wouldn't be familiar with the current generation of Devereauxes. All of us are interested about improving our country and the life of our citizens."

"Unlike previous generations?" he asked, thinking of his biological father, who, from everything he'd read, was a shameless playboy.

Stefan's facial expression closed. "Every generation has their emphasis. We can either be inspired by what they did or didn't do or spend our lives complaining about it. I sense that you're a man of action rather than the kind to sit around grumbling. Perhaps we have that in common."

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0 of 0 people found the following review helpful.
How To Catch a Prince
By Carol H Patterson
The fact that someone was able to find a family in another country and become a part of a family was good It was also neat that he found love with someone whom he had known for a while was a nice weave into the story

0 of 0 people found the following review helpful.
Wonderful!
By K Kristan
I love the Chantaine series, and am always excited when a new one is coming out. If you enjoyed the others, you will love this one. If you haven't read the rest, you won't be lost, but you will probably feel the urge to buy them. I think I read number 2 or 3 first, then had to buy everything else.

0 of 1 people found the following review helpful.
A hit
By Sherri
Great book, good flow for the story line and good characters to keep you turning the page. Looking forward to more books in the series.

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Sabtu, 18 September 2010

[K936.Ebook] Download PDF First Four Books Caesar's Commentaries on the Gallic War, by Albert Harkness

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First Four Books Caesar's Commentaries on the Gallic War, by Albert Harkness

  • Sales Rank: #5608947 in Books
  • Published on: 1901
  • Binding: Hardcover

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Rapid Review of Radiology (Medical Rapid Review Series), by Shahid Hussain, Sherif Aaron Abdel Latif, Adrian David Hall

As in all specialties, learning in radiology is a life long process but for radiologists in training there is a vast amount of information to assimilate. In this book the authors have compiled 191 cases to help the reader with the practical aspects of image recognition and differential diagnosis.

The selection of cases is broad enough to provide an introduction for some readers, with more testing cases for those in the later stages of training. Each self-test case is presented with an image, or set of images, together with the pertinent clinical details. The solution and explanation is presented over the page along with differential diagnoses that logically derive from the images and history. The correct diagnosis is followed by discussion of the underlying problem, strategy points and main imaging findings.

The book contains 500 images including X-rays, ultrasound, CT, MRI, interventional techniques and nuclear medicine. It is of value to radiologists in training and other health professionals wishing to improve their radiological skills, and is the first book for the FRCR Part 2B exam.

  • Sales Rank: #2042743 in Books
  • Published on: 2010-05-30
  • Original language: English
  • Number of items: 1
  • Dimensions: .70" h x 7.60" w x 10.20" l, 2.33 pounds
  • Binding: Paperback
  • 352 pages

Review

Despite its small size, this case-based review of diagnostic radiology is remarkably comprehensive... Overall, this book is of very high quality and it would be quite useful for senior radiology trainees in the U.K. and radiology residents preparing for American Board of Radiology exams. (5 stars)
―Dana Smetherman, MD, Ochsner Clinic Foundation, Doody's Review Service

From the Back Cover

In this book the author has compiled a selection of cases covering many aspects of radiology to help trainees with the practical aspects of image recognition and formulating a differential diagnosis. The selection of cases is broad enough to provide an introduction for some readers, with more testing cases for those in the later stages of training. Each self-test case is presented with an image, or set of images, together with the pertinent clinical details. The solution and explanation is presented over the page along with differential diagnoses that logically derive from the images and history. The correct diagnosis is followed by a discussion of the underlying diagnosis with teaching points and main imaging findings, plus any other important factors emerging from the discussion. The book contains 423 images including X-rays, ultrasound, CT, MRI, interventional techniques and nuclear medicine. It will be useful to radiologists in training and other health professional wishing to improve their radiological skills.

About the Author
Russells Hall Hospital, Dudley, West Midlands, UK.

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2 of 2 people found the following review helpful.
Very Good book for the FRCR IIB
By Dr. Muhammad
I liked most of the different cases
but too much talking in discussion after every case
I know a lot of ppl will like that but for me i liked the differential diagnoses and practical tips most.

1 of 1 people found the following review helpful.
Well done!
By Los Libros
I was looking for another general case book and test prep book to supplement Top 3. I happened to see this one and bought the kindle edition. I like the price, the images are decent quality (and so often on exams the pictures are not great resolution anyway), and the case mix is about right--not too hard not too easy. I like that the cases are presented as unknowns, followed by a solid succinct description of the findings (as if a report), and then a diagnosis and the differential. At the end there is a discussion of the diagnoses and some helpful tips. Well worth the money!

0 of 1 people found the following review helpful.
We need more books like this
By moataz abdelmagid
Every one who is going to FRCR 2B should have this book. Thanks alot for the authers.

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Jumat, 17 September 2010

[Q641.Ebook] PDF Ebook Lonely Planet Pocket Prague (Travel Guide), by Lonely Planet, Mark Baker

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Lonely Planet Pocket Prague (Travel Guide), by Lonely Planet, Mark Baker

Lonely Planet: The world's leading travel guide publisher

Lonely Planet's Pocket Prague is your passport to the most relevant, up-to-date advice on what to see and skip, and what hidden discoveries await you. Take in Prague's Gothic architecture, hang out an ornate cafe or explore the grand Prague castle; all with your trusted travel companion. Get to the heart of the best of Prague and begin your journey now!

Inside Lonely Planet's Pocket Prague:

  • Full-colour maps and images throughout
  • Highlights and itineraries help you tailor your trip to your personal needs and interests
  • Insider tips to save time and money and get around like a local, avoiding crowds and trouble spots
  • Essential info at your fingertips - hours of operation, phone numbers, websites, transit tips, prices
  • Honest reviews for all budgets - eating, sleeping, sight-seeing, going out, shopping, hidden gems that most guidebooks miss
  • Free, convenient pull-out Prague map (included in print version), plus over 16 colour neighbourhood maps
  • User-friendly layout with helpful icons, and organised by neighbourhood to help you pick the best spots to spend your time
  • Covers Hradcany, Mala Strana, Stare Mesto, Nove Mesto, Petrin Hill, Old Town Square, Wenceslas Square, Vinohrady, Zizkov and more

The Perfect Choice: Lonely Planet's Pocket Prague is a colorful, easy-to-use and handy guide that literally fits in your pocket, provides on-the-go assistance for those seeking only the can't-miss experiences to maximise a quick trip experience.

  • Looking for a comprehensive guide that recommends both popular and offbeat experiences, and extensively covers all of Prague's neighbourhoods? Check out Lonely Planet's Prague & the Czech Republic guide.
  • Looking for more extensive coverage? Check out Lonely Planet's Eastern Europe guide for a comprehensive look at all the region has to offer.

Authors: Written and researched by Lonely Planet and Mark Baker.

About Lonely Planet: Since 1973, Lonely Planet has become the world's leading travel media company with guidebooks to every destination, an award-winning website, mobile and digital travel products, and a dedicated traveller community. Lonely Planet covers must-see spots but also enables curious travellers to get off beaten paths to understand more of the culture of the places in which they find themselves.

  • Sales Rank: #90742 in Books
  • Published on: 2014-12-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 6.02" h x .43" w x 4.17" l, .0 pounds
  • Binding: Paperback
  • 176 pages

About the Author

Mark Baker is Group Editor of GMC Publications' portfolio of woodworking magazines. He has written several books on woodworking and tours and demonstrates around the world.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Just about worth having but no great shakes.
By Frances Hutner
The little maps were confusing. I could not find the specific sights and locations written up on related pages on the maps themselves. It also very often mentioned something worth seeing without giving a street. The write-ups were too general and only gave a vague idea of where to go and what to do. Just about worth having but no great shakes.

0 of 0 people found the following review helpful.
Not thrilled with this guide.
By akp173
This is the first time we have been disappointed with a Lonely Planet Guide. Some of the recommendations were not good. It is highly unlikely we will purchase another Lonely Planet Guide

0 of 0 people found the following review helpful.
Do more -- this one is fabulous!
By margaret siegel
i loved prague and exploring all the neighborhoods, with lots of useful info in a book small enough to tuck into my handbag and big enough to read!

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Selasa, 14 September 2010

[Z484.Ebook] Free Ebook National Geographic Almanac of American History, by James Miller, John Thompson

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National Geographic Almanac of American History, by James Miller, John Thompson

Featuring stunning images, revealing maps, historic facts, and concise analysis, the National Geographic Almanac of American History is carefully balanced to provide readers with a deeper comprehension of United States history.

The Almanac is unparalleled in its reader-friendly format: the book's four major sections are enhanced by a thorough table of contents, a detailed index, and bibliography, plus a feature on how to use the book. Section 1 explores America's geologic makeup and answers the question, "How was the land responsible for the way in which America developed?" Milestones comprise section 2: Twelve essays discuss how America evolved to become the global leader it is today. Section 3 covers the major eras in America's history, beginning with the earliest Native Americans. The final section of the book covers: Leaders, Wars, Religion and Beliefs, Presidents, and finally, Milestone Documents, including the Declaration of Independence, the Emancipation Proclamation, the Gettysburg Address, and more.

With an introduction by Hugh Ambrose, historian and a founding director of The National D-Day Museum, the National Geographic Almanac of American History is a timely and essential resource that every American should own.

  • Sales Rank: #808392 in Books
  • Brand: Brand: National Geographic
  • Published on: 2005-12-06
  • Released on: 2005-12-06
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.51" h x 1.20" w x 7.74" l, 2.68 pounds
  • Binding: Hardcover
  • 384 pages
Features
  • ISBN13: 9780792283683
  • Notes: 100% Satisfaction Guarantee. Tracking provided on most orders. Buy with Confidence! Millions of books sold!

About the Author
James Miller earned his Ph.D. in history from Indiana University. After teaching at Richard Stockton College of New Jersey, he was an editor in economics and history. He lives in Charlottesville, Virginia and is currently writing a biography of a Revolutionary War hero.

John Thompson is the author of six National Geographic books, and is currently researching a book on Benedict Arnold's march to Quebec. He lives with his family in Charlottesville, Virginia.

Hugh Ambrose currently serves as Historical Consultant for a miniseries about WWII being developed by Stephen Spielberg, Tom Hanks, and HBO. He is a Founding Board Member of The National D-Day Museum in New Orleans where he lives.

Most helpful customer reviews

51 of 53 people found the following review helpful.
Must have for all ages!
By A. M. Hylton
I had borrowed this book from our local library and was very impressed. There's so much information in it and so many great pictures...it is worth having on your shelf and you will refer to it often as you look up historical words or questions you run into, your children can use it for school...It is the only book of this kind, that I could find, that has the entire history and is not concentrating on just one time-period or subject abt. American history. I also bought the "world history" one from National Georaphic. It is a great price and I haven't seen it at this price anywhere else (trust me I've done some research before buying).

9 of 11 people found the following review helpful.
Beautifully illustrated reference book
By Z Hayes
The National Geographic Almanac of American History makes a wonderful reference book on American history if one is looking for one title that covers American history from prehistory to the present. The book is very user-friendly and well-organized, and is divided into the following:
The Land
Milestones [covering immigration, religion, rise of democracy, language, legal system,slavery, industry, social reform, conservation and environment, civil rights, space race, and global mission]
Major Eras [from prehistory - present]
At a Glance
Appendix
Recommended reading
Index
Illustrations credits

Though I wouldn't say this book is exhaustive in its scope, it is wide and the work is enhanced by more than 200 illustrations and maps. The essays that cover some milestone events are insightful and the illustrated time lines of important events are very useful. For those who like to read a history book with lavish illustrations, this book does an admirable job and is well-worth the money, especially at the discounted rate offered here. It makes an excellent supplementary reference tool for students, history aficionados, and reference book collectors, and would enhance any personal library. A great companion work to this would be the "Almanac of World History" also by National Geographic.

9 of 11 people found the following review helpful.
Choppily written
By An Amazonian
This book seems to have been written to run about 500 pages before it was cut down to its final length of 338 pages. many of the sections I've read have been difficult to truly understand--sometimes the authors makes claims that need more explanation, and other times the sentences or paragraphs seem to be non sequitors. Great images, though.

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[A295.Ebook] Ebook Free Chronic Disease Epidemiology, Prevention, and Control, by Patrick L. Remington, MD, MPH, Ross C. Brownson, PhD, Mark V. Wegner

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Chronic Disease Epidemiology, Prevention, and Control, by Patrick L. Remington, MD, MPH, Ross C. Brownson, PhD, Mark V. Wegner

Chronic Disease Epidemiology and Control, Fourth Edition provides an overview of current knowledge and best practices in the prevention and control of major chronic diseases and their risk factors. Chapter authors highlight many public health successes in which evidence-based interventions have resulted in improved health and the reduction or elimination of disparities. This book tackles some of the most important and vexing public health problems of our time, including how to cope with the rising tide of chronic illness.

  • Sales Rank: #77882 in Books
  • Published on: 2016-11-17
  • Original language: English
  • Dimensions: 8.90" h x 1.70" w x 6.00" l,
  • Binding: Paperback
  • 1188 pages

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Kamis, 09 September 2010

[G873.Ebook] Ebook Guide to Mutation Detection, by Human Genome Organization (HUGO)

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Guide to Mutation Detection, by Human Genome Organization (HUGO)

As genomic science and potential gene therapies continue to develop, the detection of mutations plays an increasingly central role in diverse areas of biology. With innumerable detection techniques available spanning multiple disciplines, the choice of the best method for a particular study can prove exceedingly difficult. Complexity, equipment requirements, cost, and throughput are all factors to consider, along with the huge amount of information already available through genome sequencing projects.
An essential go-to for informed decision-making, the Guide to Mutation Detection is the only single source for the theory and practice of mutation analysis needed to design an experiment. User-friendly, concise, and expertly edited by recognized leaders in the field, the text provides a cutting-edge reference that is still accessible to those with no experience in mutation analysis.
The coverage is divided into two sections, with the first section reviewing such topics as:
* Key technologies
* Mutation scanning
* Cleavage
* Quality control
* High throughput approaches
* Databases
* Nomenclatures
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* Tag-array minisequencing
* Electronic hybridization
* Pyrosequencing
* Fluorescent Single-Stranded Conformation Polymorphism (SSCP)
* Denaturing High-Performance Liquid Chromatography (DHPLC)
* Array Comparative Genomic Hybridization (ACGH)
* Microplate Array Diagonal Gel Electrophoresis (MADGE)
Throughout the text, the emphasis remains on practical applications. The detailedprotocols derive from the well-regarded Human Genome Organization (HUGO) training course, particularly those in Montpellier, France, 2002, organized by Mirielle Claustres, Johan den Dunnen, and Graham Taylor. Useful appendices contain important safety data, supplier lists, and bioinformatics resources.
Up-to-date, user friendly, and comprehensive, the Guide to Mutation Detection is an invaluable resource for students and practitioners working across a wide range of genetics-related disciplines.

  • Sales Rank: #5808173 in Books
  • Published on: 2005-02-03
  • Ingredients: Example Ingredients
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.04" h x .61" w x 7.01" l, 1.28 pounds
  • Binding: Paperback
  • 330 pages

Review
"…a useful tool…" (American Journal of Human Genetics, August 2005)

“…an honest attempt to assemble useful and practical information within this book.” (ChemBioChem, 2005; Vol.6; 6)

From the Back Cover
As genomic science and potential gene therapies continue to develop, the detection of mutations plays an increasingly central role in diverse areas of biology. With innumerable detection techniques available spanning multiple disciplines, the choice of the best method for a particular study can prove exceedingly difficult. Complexity, equipment requirements, cost, and throughput are all factors to consider, along with the huge amount of information already available through genome sequencing projects.

An essential go-to for informed decision-making, the Guide to Mutation Detection is the only single source for the theory and practice of mutation analysis needed to design an experiment. User-friendly, concise, and expertly edited by recognized leaders in the field, the text provides a cutting-edge reference that is still accessible to those with no experience in mutation analysis.

The coverage is divided into two sections, with the first section reviewing such topics as:

  • Key technologies
  • Mutation scanning
  • Cleavage
  • Quality control
  • High throughput approaches
  • Databases
  • Nomenclatures
The second section focuses on step-by-step protocols and discussion of methods, including:
  • Tag-array minisequencing
  • Electronic hybridization
  • Pyrosequencing
  • Fluorescent Single-Stranded Conformation Polymorphism (SSCP)
  • Denaturing High-Performance Liquid Chromatography (DHPLC)
  • Array Comparative Genomic Hybridization (ACGH)
  • Microplate Array Diagonal Gel Electrophoresis (MADGE)

Throughout the text, the emphasis remains on practical applications. The detailedprotocols derive from the well-regarded Human Genome Organization (HUGO) training course, particularly those in Montpellier, France, 2002, organized by Mirielle Claustres, Johan den Dunnen, and Graham Taylor. Useful appendices contain important safety data, supplier lists, and bioinformatics resources.

Up-to-date, user friendly, and comprehensive, the Guide to Mutation Detection is an invaluable resource for students and practitioners working across a wide range of genetics-related disciplines.

About the Author
Dr. Graham R. Taylor is Scientific Director of the Yorkshire Regional DNA Laboratory and Technical Director of the ICRF core mutation detection facility. He also holds an appointment as senior associate lecturer at the Leeds University School of Medicine. He is organizer of the mutation detection training course program run by the Human Genome Organization. Dr. Ian N. M. Day is Lister Institute Professor and Head of the Department of Human Genetics and Director of the Human Genetics Research Division at the University of Southampton.

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Sabtu, 04 September 2010

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